Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775893 | 0.96 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2APAF1 | |
| SCHEMBL4773614 | 0.82 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2APAF1 | |
| SCHEMBL4770133 | 0.81 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2POLBTDP1LMNA | |
| SCHEMBL4776209 | 0.81 | LMNA (0.41) | MAPTSMN1; SMN2GAALMNAALDH1A1 | |
| SCHEMBL4773953 | 0.79 | POLB (0.40) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL2574294 | 0.76 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2POLBTDP1LMNA | |
| SCHEMBL4767732 | 0.76 | HTR7 (0.43) | NPC1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL4773502 | 0.74 | MGMT (0.38) | MAPTSMN1; SMN2POLBGAALMNA | |
| SCHEMBL4775385 | 0.74 | POLB (0.41) | MAPTSMN1; SMN2POLBTDP1LMNA | |
| SCHEMBL4772531 | 0.74 | POLB (0.41) | MAPTNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |