Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 2/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774663 | 0.79 | CENPE (0.44) | CENPECCR3KIFC1MAP4K4MINK1 | |
| SCHEMBL3461137 | 0.75 | CENPE (0.44) | CENPEKIFC1P2RX3KCNQ3KCNQ2 | |
| SCHEMBL13161592 | 0.75 | CENPE (0.44) | CENPEKIFC1P2RX3KCNQ3KCNQ2 | |
| SCHEMBL3461182 | 0.74 | DHODH (0.46) | CENPEKIFC1P2RX3KCNQ3KCNQ2 | |
| SCHEMBL13161874 | 0.74 | DHODH (0.46) | CENPEKIFC1P2RX3KCNQ3KCNQ2 | |
| SCHEMBL13625049 | 0.73 | CENPE (0.41) | CENPEKIFC1P2RX3KCNQ3KCNQ2 | |
| SCHEMBL4767596 | 0.72 | CENPE (0.44) | CENPECCR3KIFC1P2RX3MAP4K4 | |
| SCHEMBL13707933 | 0.71 | CENPE (0.59) | CENPEKIFC1 | |
| SCHEMBL3461844 | 0.70 | CENPE (0.43) | CENPEKIFC1P2RX3KCNQ3KCNQ2 | |
| SCHEMBL3224472 | 0.70 | CENPE (0.43) | CENPEKIFC1P2RX3KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742907-A4 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1742907-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005107762-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2005-11-17 | — | — | WO | disclosed |