Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | APP | P05067 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.72 |
| ▸ | CTSL | P07711 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Methoxy-Acetophenone SCHEMBL4774853 | 0.92 | MEN1 (0.65) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL25205853 | 0.91 | APP (0.75) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL25196696 | 0.87 | MEN1 (0.63) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL25214779 | 0.86 | MEN1 (1.00) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL25214812 | 0.86 | MEN1 (1.00) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL9420980 | 0.85 | MAPT (0.72) | MEN1KMT2ALMNAALDH1A1ABCG2 | |
| SCHEMBL14692566 | 0.85 | MAPT (0.72) | MEN1KMT2ALMNAALDH1A1ABCG2 | |
| SCHEMBL363768 | 0.85 | LMNA (0.63) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL5915595 | 0.84 | MEN1 (0.59) | MEN1KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL28497546 | 0.84 | MEN1 (0.68) | MEN1KMT2ALMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889617-A1 | Triphenyl modified 5-membered heterocycles and their use as anticancer and antiflammatory agents | Freie Universität Berlin (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2008006626-A1 | TRIPHENYL MODIFIED 5-MEMBERED HETEROCYCLES AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | FREIE UNIVERSITÄT BERLIN (DE) | 2008-01-17 | — | — | WO | disclosed |