Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL4778932 | 1.00 | HTR2A (0.48) | HTR2ASMN1; SMN2CYP2A6TAAR1LOXL2 | |
| SCHEMBL4057742 | 0.87 | CES2 (0.41) | KEAP1GABBR2GABBR1MAPK1EPHX1 | |
| SCHEMBL900143 | 0.87 | CES2 (0.41) | KEAP1GABBR2GABBR1MAPK1EPHX1 | |
| SCHEMBL3912386 | 0.87 | CES2 (0.41) | KEAP1GABBR2GABBR1MAPK1EPHX1 | |
| SCHEMBL3159714 | 0.80 | CFD (0.38) | GABBR2GABBR1EPHX1 | |
| Armodafinil SCHEMBL34489 | 0.77 | CYP2D6 (0.44) | SMN1; SMN2GABBR2GABBR1HDAC3MAPK1 | |
| Modafinil SCHEMBL34488 | 0.77 | CYP2D6 (0.44) | SMN1; SMN2GABBR2GABBR1HDAC3MAPK1 | |
| (S)-Modafinil SCHEMBL1403524 | 0.77 | CYP2D6 (0.44) | SMN1; SMN2GABBR2GABBR1HDAC3MAPK1 | |
| Modafinil SCHEMBL3238686 | 0.77 | CYP2D6 (0.44) | SMN1; SMN2GABBR2GABBR1HDAC3MAPK1 | |
| Modafinil SCHEMBL1560974 | 0.77 | CYP2D6 (0.44) | SMN1; SMN2GABBR2GABBR1HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911739-A3 | Crystalline form of (S)-2-phenylethylammonium (R)-diphenyl-methanesulphinyl-acetate | Dipharma Francis S.r.l. (IT) | 2008-09-17 | — | — | EP | disclosed |
| EP-1911739-A2 | Crystalline form of (S)-2-phenylethylammonium (R)-diphenyl-methanesulphinyl-acetate | Dipharma Francis S.r.l. (IT) | 2008-04-16 | — | — | EP | disclosed |