Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 4/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1251713 | 0.82 | TAS1R3 (0.39) | — | |
| Hydrochloric Acid SCHEMBL30903259 | 0.81 | TAS1R3 (0.38) | — | |
| SCHEMBL13408235 | 0.77 | GAA (0.34) | MAPT | |
| Hydrochloric Acid SCHEMBL1253764 | 0.77 | GAA (0.34) | MAPT | |
| Hydrochloric Acid SCHEMBL1253765 | 0.77 | GAA (0.34) | MAPT | |
| SCHEMBL23532043 | 0.76 | EGFR (0.34) | — | |
| SCHEMBL26167937 | 0.72 | TAS1R3 (0.37) | — | |
| SCHEMBL1253825 | 0.71 | — | — | |
| SCHEMBL1253822 | 0.71 | — | — | |
| SCHEMBL12810668 | 0.71 | CRHR1 (0.40) | MTNR1AMTNR1BMAPTCMA1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973902-A2 | 3-HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | Affinium Pharmaceuticals, Inc. (CA) | 2008-10-01 | — | — | EP | claimed |
| WO-2007067416-A2 | HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2007-06-14 | — | — | WO | claimed |