Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27865820 | 1.00 | ACHE (0.69) | ACHELMNATSHRALOX12KIF11 | |
| Toluene SCHEMBL28417753 | 0.97 | ACHE (0.65) | ACHELMNATSHRALOX12KIF11 | |
| Toluene SCHEMBL27566182 | 0.97 | ACHE (0.65) | ACHELMNATSHRALOX12KIF11 | |
| Toluene SCHEMBL27303227 | 0.88 | LMNA (0.61) | ACHELMNATSHRALOX12KIF11 | |
| Toluene SCHEMBL3861980 | 0.88 | ACHE (0.69) | ACHELMNATSHRALOX12KIF11 | |
| Toluene SCHEMBL6697996 | 0.87 | ACHE (0.79) | ACHELMNATSHRALOX12TP53 | |
| Toluene SCHEMBL27301017 | 0.86 | LMNA (0.58) | ACHELMNATSHRALOX12KIF11 | |
| Toluene SCHEMBL27660767 | 0.85 | ACHE (0.65) | ACHELMNATSHRALOX12KIF11 | |
| Toluene SCHEMBL10458549 | 0.84 | ACHE (0.73) | ACHELMNATSHRALOX12TP53 | |
| Toluene SCHEMBL991792 | 0.84 | ACHE (0.73) | ACHELMNATSHRALOX12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958487-A | Benzoic acid derivatives as eif4e inhibitors | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |
| CN-102471338-B | Novel azaheterocyclic compounds | MERCK PATENT GMBH | 2014-07-02 | — | — | CN | disclosed |
| CN-102498095-A | Indoline derivatives | TOKYO INST TECH | 2012-06-13 | — | — | CN | disclosed |
| CN-102471338-A | Novel azaheterocyclic compounds | MERCK PATENT GMBH | 2012-05-23 | — | — | CN | disclosed |
| CN-100465230-C | Method for producing polymer material | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-03-04 | — | — | CN | disclosed |
| CN-100381937-C | Organophotoreceptor with charge transport material having a thiiranyl group | SAMSUNG ELECTRONICS CO LTD (KR) | 2008-04-16 | — | — | CN | disclosed |
| CN-101119962-A | Selective Cleavage of Substituted Bisbenzylamides and Bisbenzylamines | BASF AG (DE) | 2008-02-06 | — | — | CN | disclosed |
| WO-2008005942-A2 | ACTIVATABLE PROBES AND METHODS OF USE | THE GOVT. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH AND HUMAN SERVICES. (US) | 2008-01-10 | — | — | WO | disclosed |
| CN-1304433-C | Process for producing modified polymer, modified polymer obtained by the process, and rubber composition | BRIDGESTONE CORP (JP) | 2007-03-14 | — | — | CN | disclosed |
| CN-1871008-A | Triazolo-pyridazine compounds and derivatives thereof useful in the treatment of neuropathic pain | MERCK & CO INC (US) | 2006-11-29 | — | — | CN | disclosed |
| CN-1649870-A | 7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases | ACTELION PHARMACEUTICALS LTD (CH) | 2005-08-03 | — | — | CN | disclosed |
| CN-1646576-A | Process for producing modified polymer, modified polymer obtained by the process, and rubber composition | BRIDGESTONE CORP (JP) | 2005-07-27 | — | — | CN | disclosed |
| CN-1637624-A | Organophotoreceptor with charge transport material having a thiiranyl group | SAMSUNG ELECTRONICS CO LTD (KR) | 2005-07-13 | — | — | CN | disclosed |
| CN-1164650-C | Process for preparation of polyphenylether | ������ѧ��ʽ���� | 2004-09-01 | — | — | CN | disclosed |
| CN-1151148-C | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LGCI��ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| CN-1346353-A | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LG CHEMICAL LTD (KR) | 2002-04-24 | — | — | CN | disclosed |
| CN-1329102-A | Process for preparation of polyphenylether | MITSUBISHI GAS CHEMICAL CORP (JP) | 2002-01-02 | — | — | CN | disclosed |
| EP-0131542-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-04-19 | — | — | EP | disclosed |
| US-4818247-A | COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |
| CN-85106365-A | Racemic half-ester resolution process | — | 1987-03-18 | — | — | CN | disclosed |