Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749094 | 0.95 | KDM2B (0.34) | KDM2BMGLLCHRNB4CHRNA3MEN1 | |
| SCHEMBL4752015 | 0.85 | KIF11 (0.34) | KDM2BMGLLMEN1KMT2AOPRM1 | |
| SCHEMBL4752024 | 0.85 | KIF11 (0.34) | KDM2BMGLLMEN1KMT2AOPRM1 | |
| SCHEMBL4774984 | 0.85 | KDM2B (0.35) | KDM2BMGLLOPRM1OPRD1OPRK1 | |
| SCHEMBL4751355 | 0.85 | KDM2B (0.33) | KDM2BMGLLMEN1KMT2AOPRM1 | |
| SCHEMBL4751290 | 0.85 | ESRRG (0.34) | KDM2BMEN1KMT2A | |
| SCHEMBL4751349 | 0.85 | KDM2B (0.33) | KDM2BMGLLMEN1KMT2AOPRM1 | |
| SCHEMBL4019234 | 0.85 | SCN9A (0.31) | KDM2B | |
| SCHEMBL4779051 | 0.85 | KDM4E (0.36) | KDM2BMGLLMEN1KMT2AOPRM1 | |
| SCHEMBL4751597 | 0.85 | DRD3 (0.33) | KDM2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |