Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 8/20 | 0.32 |
| ▸ | DRD1 | P21728 | 8/20 | 0.32 |
| ▸ | DRD4 | P21917 | 8/20 | 0.32 |
| ▸ | DRD5 | P21918 | 8/20 | 0.32 |
| ▸ | DRD3 | P35462 | 8/20 | 0.32 |
| ▸ | DRD2 | P14416 | 7/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774948 | 0.95 | KDM2B (0.35) | KDM2BMGLLCHRNB4CHRNA3MEN1 | |
| SCHEMBL4752024 | 0.88 | KIF11 (0.34) | KDM2BHTR1ADRD1DRD4DRD5 | |
| SCHEMBL4751290 | 0.88 | ESRRG (0.34) | KDM2BHTR1ADRD1DRD4DRD5 | |
| SCHEMBL4751355 | 0.88 | KDM2B (0.33) | KDM2BHTR1ADRD1DRD4DRD5 | |
| SCHEMBL4751349 | 0.88 | KDM2B (0.33) | KDM2BHTR1ADRD1DRD4DRD5 | |
| SCHEMBL4752015 | 0.88 | KIF11 (0.34) | KDM2BHTR1ADRD1DRD4DRD5 | |
| SCHEMBL4749105 | 0.87 | MET (0.36) | KDM2BHTR1ADRD1DRD4DRD5 | |
| SCHEMBL4751597 | 0.87 | DRD3 (0.33) | KDM2BHTR1ADRD1DRD4DRD5 | |
| SCHEMBL4749472 | 0.86 | MGLL (0.32) | KDM2BMGLLCHRNB4CHRNA3 | |
| SCHEMBL4749137 | 0.85 | ACHE (0.35) | HTR1ADRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |