Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPM1 | P06748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5322809 | 0.89 | MAPT (0.52) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4777795 | 0.82 | P2RX4 (0.48) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL97864 | 0.75 | PPARG (0.49) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL4836238 | 0.75 | FFAR1 (0.41) | FFAR1PPARAPPARGMAPT | |
| SCHEMBL97465 | 0.74 | FFAR1 (0.46) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL4773991 | 0.72 | PSEN1 (0.41) | FFAR1PPARGMAPTALDH1A1 | |
| SCHEMBL9570635 | 0.72 | MAPT (0.53) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL4778666 | 0.71 | FFAR1 (0.48) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL13846789 | 0.71 | ALDH1A1 (0.41) | FFAR1PPARAPPARGMAPTALDH1A1 | |
| SCHEMBL8685830 | 0.71 | PPARG (0.47) | FFAR1PPARAPPARGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |