Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707732 | 0.90 | KDM4E (0.39) | MCL1HTTHSD17B10MEN1KMT2A | |
| SCHEMBL4707294 | 0.90 | HTT (0.43) | MCL1HTTHSD17B10TLR9TLR8 | |
| SCHEMBL4707694 | 0.86 | PDK2 (0.40) | MCL1HTTHSD17B10MEN1KMT2A | |
| SCHEMBL4708847 | 0.86 | HTT (0.46) | MCL1HTTHSD17B10TLR9TLR8 | |
| SCHEMBL4706833 | 0.84 | MCL1 (0.46) | MCL1HTTHSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4520019 | 0.79 | MCL1 (0.46) | MCL1HTTHSD17B10TLR9TLR8 | |
| SCHEMBL4510893 | 0.78 | KDM4E (0.40) | MCL1HTTHSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4516276 | 0.78 | MCL1 (0.49) | MCL1HTTHSD17B10MEN1KMT2A | |
| SCHEMBL4778114 | 0.77 | KDM4E (0.42) | MCL1HTTMEN1KMT2AKDM4E | |
| SCHEMBL4778117 | 0.77 | KDM4E (0.42) | MCL1HTTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008000818-A1 | FLUORINATED INDOLEAMIDES USEFUL AS LIGANDS OF THE ORL-1 RECEPTOR | BRANE DISCOVERY S.R.L. (IT) | 2008-01-03 | — | — | WO | claimed |