SCHEMBL4775178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4779235	0.94	MAPT (0.52)	AKT1AKT2AKT3HDAC8MC4R
	SCHEMBL4793769	0.92	MAPT (0.57)	AKT1AKT2AKT3MC4RMEN1
	SCHEMBL4773546	0.90	MC4R (0.61)	AKT1MC4RMEN1ALDH1A1KMT2A
	SCHEMBL4770964	0.89	MC4R (0.59)	AKT1AKT2AKT3HDAC8MC4R
	SCHEMBL4905812	0.87	MEN1 (0.53)	MC4RMEN1ALDH1A1KMT2AUSP2
	SCHEMBL4793962	0.86	AKT1 (0.59)	AKT1AKT2AKT3MC4RMEN1
	SCHEMBL4774413	0.86	AKT1 (0.55)	AKT1AKT2AKT3HDAC8MC4R
	SCHEMBL4778157	0.86	AKT1 (0.56)	AKT1HDAC8MC4RMEN1ALDH1A1
	SCHEMBL4775603	0.85	MC4R (0.59)	AKT1AKT2AKT3HDAC8MC4R
	SCHEMBL4776568	0.84	MC4R (0.50)	AKT1MC4RMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.