SCHEMBL4775258

SCHEMBL4775258

CC(=O)O[C@@H](C[CH]C[Si](C)(C)C)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3453553 0.77 CETP (0.30) CETP
SCHEMBL17993849 0.75 TSHR (0.33) CETP
SCHEMBL3453172 0.75 TSHR (0.33) CETP
SCHEMBL11550466 0.69 TSHR (0.37) CETP
SCHEMBL497899 0.69 TSHR (0.37) CETP
SCHEMBL3997040 0.68 TSHR (0.33) CETP
SCHEMBL7527175 0.67 TSHR (0.41) CETP
SCHEMBL20412554 0.67 TDP1 (0.38) CETP
SCHEMBL18116510 0.67 TSHR (0.36) CETP
SCHEMBL4774697 0.66 CASP3 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7423161-B2 Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines RHODIA CHIMIE (FR) 2008-09-09 US disclosed