SCHEMBL4775260

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4767924	0.82	TMPRSS2 (0.43)	HRH3RAB9ASMN1; SMN2TP53NPC1
	SCHEMBL4772072	0.80	HRH3 (0.39)	HRH3RAB9ASMN1; SMN2NPC1NFKB1
	SCHEMBL4775095	0.78	HRH3 (0.41)	HRH3RAB9AHRH1SMN1; SMN2TP53
	SCHEMBL4770767	0.78	HRH3 (0.42)	HRH3HRH1
	SCHEMBL4771970	0.77	HRH3 (0.40)	HRH3RAB9AHRH1SMN1; SMN2TP53
	SCHEMBL4767630	0.77	HRH3 (0.42)	HRH3RAB9AHRH1POLBNPC1
	Trifluoroacetic Acid SCHEMBL4775257	0.76	ROCK2 (0.44)	HRH3RAB9ASMN1; SMN2TP53NPC1
	SCHEMBL4769825	0.74	HRH3 (0.41)	HRH3HRH1
	SCHEMBL4771567	0.74	ROCK2 (0.46)	HRH3RAB9ASMN1; SMN2TP53NPC1
	Trifluoroacetic Acid SCHEMBL4774158	0.73	TMPRSS2 (0.55)	RAB9ASMN1; SMN2TP53NPC1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.