SCHEMBL4775732

SCHEMBL4775732

Cc1ccc(-c2ncc[nH]2)c(C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.58
MTOR P42345 1/20 0.42
ADK P55263 1/20 0.42
LMNA P02545 1/20 0.41
BRD4 O60885 1/20 0.41
NPBWR1 P48145 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 3/20 0.40
FGFR1 P11362 1/20 0.40
FGFR2 P21802 1/20 0.40
CSNK1A1 P48729 1/20 0.40
TYRO3 Q06418 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
HSP90AB1 P08238 1/20 0.38
ALPL P05186 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466815 1.00 NISCH (0.58) NISCHMTORADKLMNABRD4
SCHEMBL2036971 0.87 NISCH (0.56) NISCHMTORADKBRD4GAA
SCHEMBL31429683 0.83 NISCH (0.56) NISCHMTORADKLMNABRD4
SCHEMBL15152912 0.81 NISCH (0.46) NISCHMTORADKBRD4HSP90AB1
SCHEMBL12088041 0.81 NISCH (0.55) NISCHMTORADKLMNAGAA
SCHEMBL5914842 0.81 ADRA2A (0.49) NISCHMTORADKBRD4ALDH1A1
SCHEMBL8536858 0.81 ESR2 (0.46) NISCHMTORADKBRD4MAPT
SCHEMBL15082480 0.81 NISCH (0.55) NISCHMTORADKBRD4ALDH1A1
SCHEMBL15651168 0.81 NISCH (0.46) NISCHMTORADKBRD4GAA
SCHEMBL1074242 0.81 NISCH (0.55) NISCHMTORADKBRD4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114892188-B Electrochemical synthesis method of zolpidem 江苏农牧科技职业学院 2023-10-03 CN claimed
CN-114892188-A Method for electrochemically synthesizing zolpidem 江苏农牧科技职业学院 2022-08-12 CN claimed
EP-1814880-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL, S.A. (ES) 2007-08-08 EP claimed
WO-2006051063-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL S. A. (ES) 2006-05-18 WO claimed
CN-1529597-A Imidazo (1,2-A)_pyridine derivatives as mGLUR5 antagonists - 2004-09-15 CN claimed
CN-114892188-B Electrochemical synthesis method of zolpidem 江苏农牧科技职业学院 2023-10-03 CN disclosed
CN-114892188-B Electrochemical synthesis method of zolpidem 江苏农牧科技职业学院 2023-10-03 CN disclosed
CN-114249724-B Preparation method of zolpidem intermediate 鲁南制药集团股份有限公司 2023-05-26 CN disclosed
CN-116120309-A Preparation method of zolpidem 山东新时代药业有限公司 2023-05-16 CN disclosed
CN-114892188-A Method for electrochemically synthesizing zolpidem 江苏农牧科技职业学院 2022-08-12 CN disclosed
CN-114892188-A Method for electrochemically synthesizing zolpidem 江苏农牧科技职业学院 2022-08-12 CN disclosed
CN-114621217-A Preparation method of zolpidem 鲁南制药集团股份有限公司 2022-06-14 CN disclosed
WO-2006051063-A1 IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, COMPOSITIONS, USES AND METHODS RELATED THERETO FERRER INTERNACIONAL S. A. (ES) 2006-05-18 WO disclosed
CN-1227252-C Process for the preparation of 6-methyl-2- (4-methyl-phenyl) -imidazo [1, 2-a ] pyridine-3- (N, N-dimethyl-acetamide) and intermediates EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2005-11-16 CN disclosed
EP-1259509-B1 PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO 1,2-A]PYRIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2005-09-14 EP disclosed
EP-1539751-A1 PROCESS FOR THE PREPARATION OF IMIDAZO(1,2-A)PYRIDINE-3-ACETAMIDES Scinopharm Taiwan, Ltd. (TW) 2005-06-15 EP disclosed
CN-1529597-A Imidazo (1,2-A)_pyridine derivatives as mGLUR5 antagonists - 2004-09-15 CN disclosed
WO-2004007496-A1 PROCESS FOR THE PREPARATION OF IMIDAZO(1,2-A)PYRIDINE-3-ACETAMIDES SCINOPHARM TAIWAN, LTD. (TW) 2004-01-22 WO disclosed
CN-1413212-A Process for preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo [1,2-a] pyrimidine-3-(N,N-dimethyl-acetamide) and intermediates EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2003-04-23 CN disclosed
EP-1259509-A1 PROCESS FOR THE PREPARATION OF 6-METHYL-2-(4-METHYL-PHENYL)-IMIDAZO 1,2-A]PYRIMIDINE-3-(N,N-DIMETHYL-ACETAMIDE) AND INTERMEDIATES EGIS GYOGYSZERGYAR RT. (HU) 2002-11-27 EP disclosed