Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2381071 | 0.87 | KDM4E (0.44) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL3564916 | 0.84 | MAPT (0.48) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL3572244 | 0.81 | MAPT (0.44) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL2385324 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL3571744 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL1340064 | 0.74 | MAPT (0.41) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL2382891 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL3573768 | 0.70 | CRHR1 (0.35) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL1337357 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTNPSR1RAB9AAPAF1 | |
| SCHEMBL2384414 | 0.69 | PADI4 (0.44) | ALDH1A1MAPTNPSR1RAB9AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556382-B1 | 3-PHENYL SUBSTITUTED PYRIDOINDOLONE, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2008-05-28 | — | — | EP | claimed |