Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.49 |
| ▸ | FNTB | P49356 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13722157 | 0.74 | MAPT (0.66) | MAPTTSHRNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL8568308 | 0.72 | HDAC6 (0.56) | MAPTTSHRNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL7128049 | 0.71 | MAPT (0.71) | MAPTTSHRNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL13722057 | 0.71 | MAPT (0.61) | MAPTTSHRNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL13722563 | 0.69 | MEN1 (0.73) | MAPTALDH1A1FNTAFNTBMEN1 | |
| SCHEMBL31378972 | 0.69 | TDP1 (0.58) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27284080 | 0.69 | KMT2A (0.50) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL13034152 | 0.68 | SMN1; SMN2 (0.57) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31014072 | 0.68 | MEN1 (1.00) | MAPTALDH1A1FNTAFNTBMEN1 | |
| SCHEMBL179882 | 0.68 | MEN1 (1.00) | MAPTALDH1A1FNTAFNTBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | claimed |
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | disclosed |