SCHEMBL7128049

SCHEMBL7128049

COC(=O)CCN1c2ccccc2Sc2ccccc21

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.71
MEN1 O00255 4/20 0.71
KMT2A Q03164 4/20 0.71
ALDH1A1 P00352 2/20 0.69
LMNA P02545 1/20 0.67
KDM1A O60341 4/20 0.65
HTT P42858 1/20 0.64
FNTA P49354 4/20 0.56
FNTB P49356 4/20 0.56
TSHR P16473 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
BCHE P06276 1/20 0.55
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
POLB P06746 1/20 0.52
HDAC6 Q9UBN7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8568308 0.86 HDAC6 (0.56) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL13722157 0.85 MAPT (0.66) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL17356858 0.81 MAPT (0.51) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL7280026 0.80 NPSR1 (0.62) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL31014072 0.80 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL179882 0.80 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL18883324 0.79 NOTUM (0.54) MAPTMEN1KMT2AALDH1A1KDM1A
SCHEMBL13722563 0.79 MEN1 (0.73) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL6542868 0.79 MEN1 (0.73) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL13722057 0.79 MAPT (0.61) MAPTMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US claimed
CN-115612114-B Copolymer membrane and method for enzymatic self-assembly synthesis and application thereof 中国科学院天津工业生物技术研究所 2024-02-20 CN disclosed
CN-115612403-B Self-assembled strong-adhesion copolymer film, coating method and application 中国科学院天津工业生物技术研究所 2023-12-01 CN disclosed
EP-3625316-B1 DISPERSANTS, METHOD OF MAKING, AND USING SAME CHEVRON ORONITE CO (US) 2023-08-23 EP disclosed
CN-110621766-B Dispersant, method of manufacture and use thereof 雪佛龙奥伦耐有限责任公司 2021-12-24 CN disclosed
US-10815446-B2 Dispersants, method of making, and using same CHEVRON ORONITE COMPANY LLC (US) 2020-10-27 US disclosed
CN-110621766-A Dispersant, method of manufacture and use thereof 雪佛龙奥伦耐有限责任公司 2019-12-27 CN disclosed
US-20180334635-A1 DISPERSANTS, METHOD OF MAKING, AND USING SAME CHEVRON ORONITE COMPANY LLC 2018-11-22 US disclosed
US-6660503-B2 In aqueous solution NOVOZYMES A/S (DK) 2003-12-09 US disclosed
EP-0935692-B1 FABRIC TREATED WITH CELLULASE AND OXIDOREDUCTASE NOVOZYMES AS (DK) 2002-11-27 EP disclosed
WO-1996006930-A1 COPRINACEAE LACCASES NOVO NORDISK A/S (DK) 1996-03-07 WO disclosed
WO-1996005837-A1 USE OF N-SUBSTITUTED PHENOTHIAZINES BAYER AKTIENGESELLSCHAFT (DE) 1996-02-29 WO disclosed
US-5445755-A Containing hydrogen peroxide source, phenothiazine or phenoxazine peroxidase accelerator; inhibit dye transfer THE PROCTER & GAMBLE COMPANY (US) 1995-08-29 US disclosed
US-4225617-A PSYCHOTROPIC AGENTS LABORATOIRE L. LAFON (FR) 1980-09-30 US disclosed
US-4209524-A CENTRAL NERVOUS SYSTEM LABORATOIRE L. LAFON (FR) 1980-06-24 US disclosed
US-4209523-A TREATMENT OF THE CENTRAL NERVOUS SYSTEM LABORATOIRE L. LAFON (FR) 1980-06-24 US disclosed
US-4183951-A PSYCHOTROPIC AGENTS LABORATOIRE L. LAFON (FR) 1980-01-15 US disclosed
US-4152458-A CENTRAL NERVOUS SYSTEM, PSYCHOTROPIC AGENTS LABORATOIRE L. LAFON (FR) 1979-05-01 US disclosed
US-4151300-A CENTRAL NERVOUS SYSTEM, PSYCHOTROPIC LABORATOIRE L. LAFON (FR) 1979-04-24 US disclosed
US-4122186-A PSYCHOTROPIC AGENTS LABORATOIRE L. LAFON (FR) 1978-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 MAPT 4153/4885MEN1 4044/4885KMT2A 4375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.