Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.70 |
| ▸ | KLK1 | P06870 | 1/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778364 | 0.83 | TERT (0.58) | TAAR1KLK1KLK5FPR2TERT | |
| SCHEMBL3166154 | 0.82 | TAAR1 (1.00) | TAAR1KLK1KLK5FPR2TERT | |
| SCHEMBL4779375 | 0.81 | TERT (0.47) | TAAR1KLK1KLK5TERTPTH1R | |
| SCHEMBL2472567 | 0.79 | TAAR1 (0.70) | TAAR1KLK1KLK5FPR2TERT | |
| SCHEMBL4776719 | 0.79 | TAAR1 (0.70) | TAAR1KLK1KLK5FPR2TERT | |
| SCHEMBL6298733 | 0.79 | TAAR1 (0.70) | TAAR1KLK1KLK5FPR2TERT | |
| SCHEMBL2469427 | 0.79 | TAAR1 (0.70) | TAAR1KLK1KLK5FPR2TERT | |
| SCHEMBL2466732 | 0.79 | TAAR1 (0.70) | TAAR1KLK1KLK5FPR2TERT | |
| SCHEMBL2471283 | 0.79 | TAAR1 (0.70) | TAAR1KLK1KLK5FPR2TERT | |
| Hydrochloric Acid SCHEMBL6304644 | 0.78 | TAAR1 (0.68) | TAAR1KLK1KLK5FPR2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | claimed |
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |