Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725421 | 0.96 | POLB (0.48) | HSD17B2POLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4725427 | 0.96 | POLB (0.48) | HSD17B2POLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4777083 | 0.96 | POLB (0.48) | HSD17B2POLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4777088 | 0.96 | POLB (0.48) | HSD17B2POLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8220797 | 0.85 | USP30 (0.48) | HSD17B2POLBALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8220796 | 0.82 | POLB (0.47) | HSD17B2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL3443057 | 0.82 | POLB (0.47) | HSD17B2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL5177302 | 0.81 | DPP4 (0.46) | ALDH1A1FABP4 | |
| SCHEMBL3540440 | 0.81 | DPP4 (0.46) | ALDH1A1FABP4 | |
| SCHEMBL4777152 | 0.81 | POLB (0.41) | POLBALDH1A1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |