Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777150 | 1.00 | POLB (0.41) | POLBALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL4725192 | 0.81 | OPRD1 (0.46) | — | |
| SCHEMBL4725189 | 0.81 | OPRD1 (0.46) | — | |
| SCHEMBL4776192 | 0.81 | HSD17B2 (0.47) | POLBALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL4782508 | 0.81 | OPRD1 (0.38) | POLB | |
| SCHEMBL4777088 | 0.78 | POLB (0.48) | POLBALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL4725421 | 0.78 | POLB (0.48) | POLBALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL4777083 | 0.78 | POLB (0.48) | POLBALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL4725427 | 0.78 | POLB (0.48) | POLBALDH1A1MEN1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL4776178 | 0.74 | SLC6A2 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |