Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725421 | 1.00 | POLB (0.48) | POLBHSD17B2ALDH1A1MEN1MAPK1 | |
| SCHEMBL4777083 | 1.00 | POLB (0.48) | POLBHSD17B2ALDH1A1MEN1MAPK1 | |
| SCHEMBL4725427 | 1.00 | POLB (0.48) | POLBHSD17B2ALDH1A1MEN1MAPK1 | |
| SCHEMBL4776192 | 0.96 | HSD17B2 (0.47) | POLBHSD17B2ALDH1A1MEN1MAPK1 | |
| SCHEMBL8220796 | 0.85 | POLB (0.47) | POLBHSD17B2MEN1KMT2ATSHR | |
| SCHEMBL3443057 | 0.85 | POLB (0.47) | POLBHSD17B2MEN1KMT2ATSHR | |
| SCHEMBL4777773 | 0.83 | SPHK2 (0.50) | POLBKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4777767 | 0.83 | SPHK2 (0.50) | POLBKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4725335 | 0.83 | DRD2 (0.41) | — | |
| SCHEMBL4778947 | 0.83 | DRD2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |