Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.71 |
| ▸ | HTR1D | P28221 | 3/20 | 0.71 |
| ▸ | HTR1B | P28222 | 3/20 | 0.71 |
| ▸ | MPO | P05164 | 2/20 | 0.71 |
| ▸ | HTR2C | P28335 | 2/20 | 0.71 |
| ▸ | HTR6 | P50406 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | CTSK | P43235 | 1/20 | 0.71 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.71 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptamine SCHEMBL30426532 | 0.90 | HTR7 (0.83) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL28751439 | 0.88 | CYP1A2 (0.81) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL27094904 | 0.87 | HTR1B (0.78) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL30812535 | 0.85 | HTR7 (0.76) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL5298628 | 0.85 | HTR1B (0.76) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL28985494 | 0.85 | CYP1A2 (0.81) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL8714244 | 0.84 | HTR2A (1.00) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL26725 | 0.84 | HTR2A (1.00) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL29373222 | 0.84 | HTR2A (1.00) | HTR7CYP1A2HTR1DHTR1BMPO | |
| Tryptamine SCHEMBL29693568 | 0.84 | HTR7 (0.73) | HTR7CYP1A2HTR1DHTR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779140-B | Compounds and methods for synthesizing 5- (N-protected tryptophanyl carboxamide) -2' -deoxyuridine phosphoramidites for incorporation into nucleic acid sequences | 私募蛋白质体操作有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108779140-A | For synthesizing the Compounds and methods for for 5- (the color amino Carboxylamide of N-protected) -2 '-uracil deoxyriboside phosphoramidates being incorporated in nucleic acid sequence | 私募蛋白质体公司 | 2018-11-09 | — | — | CN | disclosed |
| EP-1902044-A1 | 5-HTX MODULATORS | Bio Medisinsk Innovasjon AS (NO) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007072-A1 | 5-HTX MODULATORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2007-01-18 | — | — | WO | disclosed |