Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946321 | 0.89 | KDM4E (0.57) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL945912 | 0.88 | KDM4E (0.67) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL4772872 | 0.87 | HTR6 (0.58) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL948577 | 0.84 | HTR6 (0.58) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL4778239 | 0.84 | HTR6 (0.60) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL947412 | 0.84 | KDM4E (0.58) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL4778090 | 0.83 | KDM4E (0.52) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL946386 | 0.83 | KDM4E (0.49) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL946643 | 0.83 | KDM4E (0.76) | HTR6KDM4EUBE2NCYP3A4CYP2D6 | |
| SCHEMBL949233 | 0.81 | KDM4E (0.52) | HTR6KDM4EUBE2NCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |