Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 15/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778240 | 0.93 | HTR6 (0.59) | KDM4EUBE2NHTR6PPARGPPARD | |
| SCHEMBL3035871 | 0.90 | HTR6 (0.59) | KDM4EUBE2NHTR6PPARGPPARD | |
| SCHEMBL946321 | 0.89 | KDM4E (0.57) | KDM4EUBE2NHTR6CYP3A4CYP2D6 | |
| SCHEMBL945912 | 0.88 | KDM4E (0.67) | KDM4EUBE2NHTR6CA2CA9 | |
| SCHEMBL4776444 | 0.86 | HTR6 (0.46) | KDM4EUBE2NHTR6CYP3A4CYP2D6 | |
| SCHEMBL4776515 | 0.86 | HTR6 (0.53) | KDM4EUBE2NHTR6PPARGPPARD | |
| SCHEMBL4776849 | 0.85 | KDM4E (0.64) | KDM4EUBE2NHTR6PPARGPPARD | |
| SCHEMBL948577 | 0.84 | HTR6 (0.58) | KDM4EUBE2NHTR6CYP3A4CYP2D6 | |
| SCHEMBL947412 | 0.84 | KDM4E (0.58) | KDM4EUBE2NHTR6CYP3A4CYP2D6 | |
| SCHEMBL4776299 | 0.83 | HTR6 (0.62) | KDM4EUBE2NHTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |