Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881403 | 0.87 | HPGD (0.56) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2878635 | 0.77 | NPC1 (0.60) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9357891 | 0.74 | RAB9A (1.00) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4878704 | 0.71 | GPR17 (0.49) | HPGDSMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL8661193 | 0.71 | TUBB4A (0.64) | HPGDCYP1A2CYP2C19SMN1; SMN2TUBB4A | |
| SCHEMBL4780752 | 0.70 | NPC1 (0.44) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15143918 | 0.68 | SMN1; SMN2 (0.79) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17422723 | 0.68 | PDGFRB (0.48) | NPC1RAB9ASMN1; SMN2DHODHKDM4E | |
| SCHEMBL5623658 | 0.68 | NPC1 (0.63) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12105957 | 0.67 | SMN1; SMN2 (0.59) | HPGDNPC1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984332-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |