Sugi Predict

Sugi Predict / Compounds / SCHEMBL477651

SCHEMBL477651

SCHEMBL477651

OC(c1ccccc1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.53
▸ TDO2 P48775 1/20 0.53
▸ IDO2 Q6ZQW0 1/20 0.53
▸ SLC6A2 P23975 6/20 0.53
▸ SLC6A4 P31645 6/20 0.53
▸ SLC6A3 Q01959 6/20 0.53
▸ KCNH2 Q12809 4/20 0.53
▸ CYP3A4 P08684 4/20 0.53
▸ CYP2D6 P10635 4/20 0.53
▸ PTPN5 P54829 4/20 0.53
▸ HTR1A P08908 1/20 0.45
▸ HTR7 P34969 1/20 0.45
▸ PLA2G1B P04054 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ ATG4B Q9Y4P1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1981717 0.85 TP53 (0.48) SLC6A2SLC6A4SLC6A3PTPN5
SCHEMBL28999637 0.82 IDO1 (0.41) IDO1TDO2IDO2SLC6A2SLC6A4
SCHEMBL28999639 0.82 CNR2 (0.43) SLC6A2SLC6A4SLC6A3KCNH2CYP3A4
SCHEMBL28999627 0.82 SLC6A4 (0.43) SLC6A2SLC6A4SLC6A3KCNH2CYP3A4
SCHEMBL17064807 0.82 CA1 (0.44) IDO1TDO2IDO2SLC6A2SLC6A4
SCHEMBL28999628 0.81 PTPN5 (0.48) SLC6A2SLC6A4SLC6A3KCNH2CYP3A4
SCHEMBL11642246 0.81 PTPN5 (0.48) SLC6A2SLC6A4SLC6A3KCNH2CYP3A4
SCHEMBL8671295 0.79 SMN1; SMN2 (0.58) CYP2D6
SCHEMBL15647693 0.78 SMN1; SMN2 (0.61) SLC6A2SLC6A4SLC6A3KCNH2CYP3A4
SCHEMBL17802412 0.78 SLC6A2 (0.49) IDO1TDO2IDO2SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119243184-A Electrochemical organic synthesis method of benzyl alcohol fluorinated product by using sulfur hexafluoride as fluorination reagent 国网安徽省电力有限公司电力科学研究院 2025-01-03 — — CN claimed
CN-113387799-B Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof 南京工业大学 2021-12-21 — — CN claimed
CN-113387799-A Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof 南京工业大学 2021-09-14 — — CN claimed
CN-119243184-B Electrochemical organic synthesis method of benzyl alcohol fluorinated product by using sulfur hexafluoride as fluorination reagent 国网安徽省电力有限公司电力科学研究院 2025-11-11 — — CN disclosed
CN-119243184-A Electrochemical organic synthesis method of benzyl alcohol fluorinated product by using sulfur hexafluoride as fluorination reagent 国网安徽省电力有限公司电力科学研究院 2025-01-03 — — CN disclosed
CN-119243184-A Electrochemical organic synthesis method of benzyl alcohol fluorinated product by using sulfur hexafluoride as fluorination reagent 国网安徽省电力有限公司电力科学研究院 2025-01-03 — — CN disclosed
CN-113387799-B Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof 南京工业大学 2021-12-21 — — CN disclosed
CN-113387799-A Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof 南京工业大学 2021-09-14 — — CN disclosed
US-20210093618-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2021-04-01 — — US disclosed
US-20210093618-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2021-04-01 — — US disclosed
US-20200108054-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2020-04-09 — — US disclosed
US-20040259912-A1 Benzine derivatives, process for preparing the same and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-12-23 — — US disclosed
EP-1437344-A1 BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-07-14 — — EP disclosed
US-5116988-A Antiepileptic WARNER-LAMBERT CO. (US) 1992-05-26 — — US disclosed
US-5053521-A 3-amino butyric acid uptake inhibitors, antiepileptic agents WARNER-LAMBERT COMPANY (US) 1991-10-01 — — US disclosed
EP-0221572-B1 N-SUBSTITUTED 3-PIPERIDINE-OR 3-PYRIDINE-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF WARNER-LAMBERT COMPANY (US) 1991-09-25 — — EP disclosed
US-4910312-A Containing 1-(2-(bis((4-trifluoromethylphenyl)methoxy)-ethyl)-substitution WARNER-LAMBERT COMPANY (US) 1990-03-20 — — US disclosed
EP-0346927-A2 Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridine-carboxylic acids and derivatives thereof WARNER-LAMBERT COMPANY (US) 1989-12-20 — — EP disclosed
US-4772615-A ANTICONVULSANT FOR TREATING EPILEPSY WARNER-LAMBERT COMPANY (US) 1988-09-20 — — US disclosed
EP-0221572-A2 N-substituted 3-piperidine-or 3-pyridine-carboxylic acids and derivatives thereof WARNER-LAMBERT COMPANY (US) 1987-05-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210093618-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF BRIX1, RDX, SULT2A1 IDO1 2403/4885TDO2 3264/4885IDO2 2404/4885
US-20040259912-A1 Benzine derivatives, process for preparing the same and use thereof HRH4, HRH2, HRH1 IDO1 953/4885TDO2 675/4885IDO2 1385/4885
US-20200108054-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF BRIX1, RDX, SULT2A1 IDO1 2403/4885TDO2 3264/4885IDO2 2404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.