Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771963 | 1.00 | PDE4B (0.33) | PDE4BSIGMAR1NR3C1DPP4 | |
| SCHEMBL4774900 | 0.86 | DPP4 (0.40) | PDE4BNR3C1DPP4 | |
| SCHEMBL4774893 | 0.86 | DPP4 (0.40) | PDE4BNR3C1DPP4 | |
| SCHEMBL4769897 | 0.85 | SIGMAR1 (0.32) | PDE4BSIGMAR1 | |
| SCHEMBL4771961 | 0.82 | PDE4B (0.35) | PDE4BDPP4 | |
| SCHEMBL4774881 | 0.79 | DPP4 (0.44) | DPP4 | |
| SCHEMBL4778806 | 0.79 | PDE4B (0.43) | PDE4B | |
| SCHEMBL27662807 | 0.78 | DPP4 (0.34) | PDE4BSIGMAR1DPP4 | |
| SCHEMBL27662806 | 0.77 | PDE10A (0.35) | PDE4BSIGMAR1 | |
| SCHEMBL4770211 | 0.76 | NR3C1 (0.33) | SIGMAR1NR3C1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763528-B1 | PYRAZOLOPYRIDINE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2008-11-26 | — | — | EP | claimed |