Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | APP | P05067 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310367 | 0.83 | MAOB (0.60) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL27747848 | 0.81 | MAOB (0.64) | MAOBRAB9ASMN1; SMN2 | |
| SCHEMBL2270908 | 0.79 | MAOB (0.69) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL18429678 | 0.79 | MAOB (0.69) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL28075228 | 0.79 | MAOB (0.75) | MAOBAPPNPC1RAB9ATDP1 | |
| SCHEMBL1068523 | 0.78 | — | — | |
| SCHEMBL20000873 | 0.76 | APP (0.80) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL7240044 | 0.76 | MAOB (0.53) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL3930569 | 0.76 | APP (0.63) | MAOBAPPNPC1RAB9APOLB | |
| SCHEMBL7240384 | 0.76 | MAOB (0.53) | MAOBAPPNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |