Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265022 | 0.91 | KDM4E (0.42) | KDM4EMAPK1HIF1AALDH1A1FAAH | |
| SCHEMBL6044936 | 0.83 | — | — | |
| SCHEMBL4744653 | 0.82 | FAAH (0.48) | CNR2ALDH1A1CNR1FAAHNAAA | |
| SCHEMBL11318606 | 0.80 | FAAH (0.52) | CNR2ALDH1A1FAAHNAAA | |
| SCHEMBL20503263 | 0.80 | FAAH (0.52) | CNR2ALDH1A1FAAHNAAA | |
| SCHEMBL23528236 | 0.80 | FAAH (0.52) | CNR2ALDH1A1FAAHNAAA | |
| SCHEMBL19970455 | 0.80 | FAAH (0.52) | CNR2ALDH1A1FAAHNAAA | |
| SCHEMBL20959807 | 0.80 | FAAH (0.52) | CNR2ALDH1A1FAAHNAAA | |
| SCHEMBL11152873 | 0.80 | FAAH (0.52) | CNR2ALDH1A1FAAHNAAA | |
| SCHEMBL11329413 | 0.80 | FAAH (0.52) | CNR2ALDH1A1FAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881825-A2 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006121831-A2 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2006-11-16 | — | — | WO | disclosed |