Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780063 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL4777781 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL4894830 | 0.97 | POLB (0.44) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL4894834 | 0.97 | POLB (0.44) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL4795657 | 0.97 | POLB (0.44) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL4021786 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL4026128 | 0.89 | MEN1 (0.45) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL4026132 | 0.89 | MEN1 (0.45) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL4022022 | 0.88 | MEN1 (0.45) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL4022026 | 0.88 | MEN1 (0.45) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |