Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835973 | 0.86 | ALDH1A1 (0.52) | CYP2C9ALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL28762510 | 0.84 | BPTF (0.52) | CYP2C9ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL1914984 | 0.84 | BPTF (0.52) | CYP2C9ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL14704709 | 0.84 | BPTF (0.52) | CYP2C9ALDH1A1L3MBTL1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL23091800 | 0.83 | BPTF (0.50) | CYP2C9ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL6274848 | 0.80 | CHRNB2 (0.50) | CYP2C9ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL13229554 | 0.79 | CYP2C9 (0.53) | CYP2C9ALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL1619341 | 0.77 | TSHR (0.52) | CYP2C9ALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL12207380 | 0.74 | CYP2C9 (0.57) | CYP2C9ALDH1A1L3MBTL1POLBKMT2A | |
| SCHEMBL11776237 | 0.74 | CYP2C9 (0.52) | CYP2C9ALDH1A1L3MBTL1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893619-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTMIAS | AstraZeneca AB (SE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006135316-A1 | New oxabispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2006-12-21 | — | — | WO | disclosed |