Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALPL | P05186 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928146 | 0.85 | LRRK2 (0.56) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL3938486 | 0.84 | KIF11 (0.51) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL3936896 | 0.82 | AKT1 (0.39) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL3924691 | 0.82 | LRRK2 (0.48) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL4013231 | 0.80 | MAPK14 (0.46) | ALDH1A1HPGD | |
| SCHEMBL3929285 | 0.79 | MEN1 (0.52) | KMT2AMEN1RAB9APOLB | |
| SCHEMBL3929248 | 0.79 | AKT1 (0.41) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL3933990 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EALPLLMNAMAPT | |
| SCHEMBL21628242 | 0.78 | KDM4E (0.65) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL3927907 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |