SCHEMBL4776948

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4778045	0.92	DPP4 (0.52)	DPP4OPRD1OPRK1FAPDPP8
	SCHEMBL4775634	0.91	OPRD1 (0.55)	DPP4OPRD1OPRK1FAPDPP8
	SCHEMBL4778103	0.90	AKT1 (0.55)	DPP4AKT1AKT2AKT3FAP
	Hydrochloric Acid SCHEMBL4909763	0.89	AKT1 (0.54)	DPP4AKT1AKT2AKT3FAP
	Hydrochloric Acid SCHEMBL4909750	0.89	AKT1 (0.54)	DPP4AKT1AKT2AKT3FAP
	SCHEMBL4770080	0.88	DPP4 (0.47)	DPP4OPRD1AKT1AKT2AKT3
	SCHEMBL4778510	0.86	AKT1 (0.50)	DPP4OPRD1AKT1AKT2AKT3
	SCHEMBL4776864	0.85	HRH2 (0.51)	DPP4FAPDPP8DPP9DPP7
	SCHEMBL4773416	0.84	DPP4 (0.47)	DPP4HPNHGFACST14OPRD1
	SCHEMBL2376093	0.82	HDAC8 (0.59)	DPP4OPRD1OPRK1FAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.