Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4772057 | 0.94 | POLB (0.47) | POLBGAAJAK1HRH3MLNR | |
| SCHEMBL4767967 | 0.85 | HRH3 (0.48) | HRH3RAB9ANPC1HRH1 | |
| SCHEMBL4768406 | 0.83 | HRH3 (0.46) | HRH3RAB9AHRH1 | |
| SCHEMBL4768724 | 0.79 | BLM (0.46) | POLBGAAHRH3MLNRRAB9A | |
| Trifluoroacetic Acid SCHEMBL4775304 | 0.78 | SLC2A1 (0.43) | POLBHRH3HRH1 | |
| SCHEMBL4767869 | 0.77 | HRH3 (0.49) | GAAHRH3MLNRRAB9ANPC1 | |
| SCHEMBL4765424 | 0.77 | HRH3 (0.47) | GAAHRH3RAB9ANPC1HRH1 | |
| SCHEMBL4772665 | 0.76 | HRH3 (0.52) | GAAHRH3RAB9ANPC1HRH1 | |
| SCHEMBL4771567 | 0.76 | ROCK2 (0.46) | GAAHRH3RAB9ANPC1 | |
| SCHEMBL4767267 | 0.75 | HRH3 (0.52) | GAAHRH3RAB9ANPC1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |