Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777063 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL30679480 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL2474284 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL2474283 | 0.90 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL6377821 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL9096012 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL30106402 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL36925 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL36926 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4ENPC1RAB9A | |
| SCHEMBL18422374 | 0.83 | CES2 (0.54) | ALDH1A1TDP1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703445-B2 | Molecular diagnostics amplification system and methods | ABBOTT POINT OF CARE INC. (US) | 2014-04-22 | — | — | US | disclosed |
| EP-1966366-A2 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I-STAT CORPORATION (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007078850-A9 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I STAT CORP (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007078850-A2 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I-STAT CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070154922-A1 | MOLECULAR DIAGNOSTICS AMPLIFICATION SYSTEM AND METHODS | I-STAT CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |