Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175096 | 1.00 | HTT (0.45) | HTTTP53MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL9170687 | 0.90 | L3MBTL1 (0.37) | HTTTP53MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL9170684 | 0.90 | L3MBTL1 (0.37) | HTTTP53MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL14254879 | 0.89 | MAPT (0.39) | HTTTP53MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL10039826 | 0.89 | MAPT (0.39) | HTTTP53MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL6932967 | 0.88 | MMP14 (0.47) | HTTMMP14ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2602717 | 0.88 | MMP14 (0.47) | HTTMMP14ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9172224 | 0.88 | HTT (0.45) | HTTTP53MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL9172233 | 0.88 | HTT (0.45) | HTTTP53MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL9172229 | 0.88 | MMP14 (0.38) | HTTTP53MMP14ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017318-A1 | OPTICAL DEVICE AND POLYMER MATERIAL WITH NONLINEAR OPTICAL PROPERTIES | PIRELLI & C. S.P.A. (IT) | 2008-02-14 | — | — | WO | disclosed |
| US-5496899-A | Crosslinkable polymer material which may be used in non-linear optics and process for obtaining it | FRANCE TELECOM (FR) | 1996-03-05 | — | — | US | disclosed |
| EP-0474402-B1 | Chromophore-containing compounds for opto-electronic applications | ICI PLC (GB) | 1995-05-24 | — | — | EP | disclosed |
| US-5290630-A | Chromophore-containing compounds for opto-electronic applications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-01 | — | — | US | disclosed |
| EP-0474402-A2 | Chromophore-containing compounds for opto-electronic applications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |