Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 15/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 15/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | DMPK | Q09013 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 1/20 | 0.38 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4725210 | 0.99 | ROCK2 (0.49) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| SCHEMBL4777272 | 0.86 | ROCK2 (0.50) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| Hydrochloric Acid SCHEMBL4725212 | 0.86 | ROCK2 (0.49) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| SCHEMBL354195 | 0.85 | ROCK1 (0.54) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| SCHEMBL353543 | 0.82 | ROCK2 (0.62) | ROCK2ROCK1EPHX2ATG4B | |
| SCHEMBL352833 | 0.80 | ROCK2 (0.49) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| SCHEMBL3656133 | 0.80 | ROCK2 (0.60) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| SCHEMBL10237499 | 0.79 | ROCK2 (0.61) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| SCHEMBL354019 | 0.79 | ROCK1 (0.68) | ROCK2ROCK1EPHX2ATG4BSGK1 | |
| SCHEMBL354438 | 0.78 | ROCK1 (0.49) | ROCK2ROCK1EPHX2ATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |