Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 7/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.51 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103608 | 0.83 | TTR (0.56) | HIF1AP4HTMP4HA1MIFALDH1A1 | |
| SCHEMBL18015585 | 0.82 | P4HTM (0.50) | P4HTMP4HA1MIFALDH1A1KDM4E | |
| SCHEMBL15103694 | 0.81 | KMO (0.59) | HIF1AP4HTMACMSDP4HA1MIF | |
| SCHEMBL29929320 | 0.80 | HIF1A (0.55) | HIF1AP4HTMP4HA1MIFALDH1A1 | |
| SCHEMBL71034 | 0.80 | HIF1A (0.55) | HIF1AP4HTMP4HA1MIFALDH1A1 | |
| SCHEMBL4780143 | 0.79 | EGLN1 (0.56) | HIF1AP4HTMP4HA1MIFALDH1A1 | |
| SCHEMBL13731115 | 0.79 | P4HTM (0.64) | HIF1AP4HTMP4HA1MIFALDH1A1 | |
| Hydrochloric Acid SCHEMBL28470042 | 0.78 | HIF1A (0.54) | HIF1AP4HTMP4HA1MIFALDH1A1 | |
| SCHEMBL2553924 | 0.77 | P4HTM (0.44) | P4HTMP4HA1MIFALDH1A1KDM4E | |
| SCHEMBL2563569 | 0.77 | KDM4C (0.52) | P4HTMP4HA1MIFALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008001160-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | claimed |
| US-20060247239-A1 | Melanin concentrating hormone antagonists | HU XIUFENG E | 2006-11-02 | — | — | US | claimed |
| CN-104311480-A | Picolinamide derivatives as kinase inhibitors | NOVARTIS AG | 2015-01-28 | — | — | CN | disclosed |
| CN-102203079-B | Pyridine carboxamide derivatives as kinase inhibitors | NOVARTIS AG | 2014-12-10 | — | — | CN | disclosed |
| EP-2132177-B1 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE | NOVARTIS AG (CH) | 2013-07-17 | — | — | EP | disclosed |
| WO-2008001160-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |
| US-20060247239-A1 | Melanin concentrating hormone antagonists | HU XIUFENG E | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247239-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | HIF1A 1549/4885P4HTM 642/4885ACMSD 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.