Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573980 | 0.86 | MAPT (0.40) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL4839135 | 0.83 | MAPT (0.39) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL5272473 | 0.82 | MAPT (0.46) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL4776998 | 0.80 | MAPT (0.45) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL4780471 | 0.80 | MAPT (0.45) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL5269908 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL5266914 | 0.79 | MAPT (0.41) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL5270452 | 0.77 | MAPT (0.38) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL5574023 | 0.76 | MAPT (0.43) | MAPTALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL5571402 | 0.76 | KDM4E (0.43) | MAPTALDH1A1HPGDCYP1A2XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009924-A2 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2008-01-24 | — | — | WO | disclosed |