Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.65 |
| ▸ | DRD4 | P21917 | 18/20 | 0.65 |
| ▸ | DRD3 | P35462 | 18/20 | 0.65 |
| ▸ | HTR2A | P28223 | 14/20 | 0.65 |
| ▸ | DRD1 | P21728 | 12/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3622140 | 0.92 | DRD2 (0.64) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3619207 | 0.90 | DRD2 (0.63) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3622453 | 0.89 | DRD2 (0.63) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3617165 | 0.88 | DRD3 (0.70) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3622028 | 0.86 | DRD2 (0.73) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3607471 | 0.85 | DRD4 (0.65) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3622814 | 0.85 | DRD3 (0.67) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3617430 | 0.85 | DRD3 (0.67) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3603449 | 0.85 | DRD3 (0.67) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3619108 | 0.85 | DRD2 (0.71) | DRD2DRD4DRD3HTR2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972628-A1 | Indolizines and aza-analog derivatives thereof as CNS active compounds | SCHWARZ PHARMA AG (DE) | 2008-09-24 | — | — | EP | disclosed |