Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.63 |
| ▸ | DRD4 | P21917 | 15/20 | 0.63 |
| ▸ | DRD3 | P35462 | 15/20 | 0.63 |
| ▸ | HTR2A | P28223 | 14/20 | 0.62 |
| ▸ | DRD1 | P21728 | 9/20 | 0.62 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619108 | 0.94 | DRD2 (0.71) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3622453 | 0.92 | DRD2 (0.63) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3622140 | 0.91 | DRD2 (0.64) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3611750 | 0.91 | DRD2 (0.76) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL4777323 | 0.90 | DRD2 (0.65) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3611309 | 0.86 | DRD2 (0.71) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3622028 | 0.85 | DRD2 (0.73) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3617165 | 0.85 | DRD3 (0.70) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3622814 | 0.85 | DRD3 (0.67) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3615568 | 0.84 | DRD2 (0.59) | DRD2DRD4DRD3HTR2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168125-A1 | INDOLIZINES AND AZA-ANALOG DERIVATIVES THEREOF AS CNS ACTIVE COMPOUNDS | DONSBACH, MARTIN (DE) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168125-A1 | INDOLIZINES AND AZA-ANALOG DERIVATIVES THEREOF AS CNS ACTIVE COMPOUNDS | INMT, AANAT, AZI2 | DRD2 123/4885DRD4 133/4885DRD3 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.