Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16829010 | 0.82 | NAMPT (0.45) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL4664237 | 0.81 | NAMPT (0.44) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL21730231 | 0.77 | NAMPT (0.47) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL29907709 | 0.77 | NAMPT (0.47) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL12578946 | 0.76 | ATR (0.47) | KCNA5NAMPTKDM4AL3MBTL1CYP3A4 | |
| SCHEMBL15804093 | 0.76 | NAMPT (0.46) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL12663061 | 0.76 | NAMPT (0.44) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL35210561 | 0.75 | NAMPT (0.46) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL17018589 | 0.75 | NAMPT (0.46) | KCNA5NAMPTKDM4AL3MBTL1NQO2 | |
| SCHEMBL15692558 | 0.75 | NAMPT (0.42) | KCNA5NAMPTKDM4AL3MBTL1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | Eli Lilly & Company (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |