Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794458 | 0.85 | EP300 (0.39) | EP300CREBBPKDM4CICAM1SELE | |
| SCHEMBL1548491 | 0.80 | KDM4C (0.43) | KDM4CKMT2AICAM1SELEALDH1A1 | |
| SCHEMBL17288212 | 0.71 | KDM4C (0.53) | KDM4CKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1548722 | 0.70 | KDM4C (0.43) | EP300CREBBPKDM4CKMT2AICAM1 | |
| SCHEMBL18106022 | 0.70 | KDM4C (0.44) | KDM4CKMT2AICAM1SELEALDH1A1 | |
| SCHEMBL4780075 | 0.70 | PTGER4 (0.50) | KMT2AALDH1A1CNR2MAPTCYP19A1 | |
| SCHEMBL1452396 | 0.69 | KDM4C (0.43) | EP300CREBBPKDM4CKMT2AICAM1 | |
| SCHEMBL31221861 | 0.69 | KDM4C (0.43) | EP300CREBBPKDM4CKMT2AICAM1 | |
| SCHEMBL15278408 | 0.66 | ICAM1 (0.39) | EP300CREBBPKDM4CKMT2AICAM1 | |
| SCHEMBL7737544 | 0.66 | KDM4C (0.43) | EP300CREBBPKDM4CKMT2AICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |