Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689666 | 0.83 | CYP19A1 (0.64) | PTGER4KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4780793 | 0.81 | PTGER4 (0.55) | PTGER4MAPTCYP19A1HDAC6LMNA | |
| SCHEMBL8156486 | 0.81 | PTGER4 (0.55) | PTGER4KMT2AMEN1ALDH1A1CYP19A1 | |
| SCHEMBL28392221 | 0.81 | P2RX4 (0.61) | PTGER4KMT2AMEN1ALDH1A1CYP19A1 | |
| SCHEMBL4775757 | 0.80 | PTGER4 (0.46) | PTGER4CYP19A1HDAC6LMNAPSMD14 | |
| SCHEMBL4779161 | 0.79 | PTGER4 (0.48) | PTGER4CYP19A1HDAC6LMNAPSMD14 | |
| SCHEMBL28179541 | 0.79 | MAPT (0.56) | PTGER4KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30676985 | 0.79 | PTGER4 (0.55) | PTGER4KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL689732 | 0.79 | PTGER4 (0.55) | PTGER4KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4793098 | 0.79 | CYP11B1 (0.44) | PTGER4ALDH1A1MAPTCYP19A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |