SCHEMBL4777823

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16982381	0.76	CAPN1 (0.89)	CAPN1CTSBCAPN9MAPK1CTSL
	SCHEMBL4777829	0.76	CAPN1 (0.79)	CAPN1CTSBCAPN9MAPK1CTSL
	SCHEMBL14067686	0.76	CAPN1 (0.79)	CAPN1CTSBCAPN9MAPK1CTSL
	SCHEMBL25896985	0.74	CAPN1 (0.76)	CAPN1CTSBCAPN9MAPK1CTSL
	SCHEMBL8219586	0.72	CAPN1 (0.81)	CAPN1CTSBCAPN9MAPK1CTSL
	E-64C SCHEMBL3281530	0.72	CAPN1 (1.00)	CAPN1CTSBCAPN9MAPK1CTSL
	E-64C SCHEMBL1121089	0.72	CAPN1 (1.00)	CAPN1CTSBCAPN9MAPK1CTSL
	E-64C SCHEMBL10933522	0.72	CAPN1 (1.00)	CAPN1CTSBCAPN9MAPK1CTSL
	E-64C SCHEMBL10750447	0.72	CAPN1 (1.00)	CAPN1CTSBCAPN9MAPK1CTSL
	E-64C SCHEMBL14067670	0.72	CAPN1 (1.00)	CAPN1CTSBCAPN9MAPK1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.