Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 10/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267447 | 0.86 | — | — | |
| SCHEMBL920032 | 0.82 | — | — | |
| SCHEMBL919602 | 0.77 | — | — | |
| SCHEMBL193152 | 0.77 | — | — | |
| SCHEMBL26068 | 0.75 | CYP1A2 (0.37) | — | |
| SCHEMBL8393739 | 0.75 | CYP1A2 (0.37) | — | |
| SCHEMBL10938577 | 0.74 | SLC6A1 (0.31) | KCNH2 | |
| SCHEMBL1794699 | 0.71 | — | — | |
| SCHEMBL1795631 | 0.71 | SHBG (0.38) | — | |
| SCHEMBL919513 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968976-A1 | SUBSTITUTED PYRAZOLO [4,3-C] PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007068619-A1 | SUBSTITUTED PYRAZOLO [4,3-C] PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-06-21 | — | — | WO | disclosed |