Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778083 | 0.77 | ALDH1A1 (0.65) | GAAUSP2ALOX15HSD17B10HDAC2 | |
| SCHEMBL13832017 | 0.65 | PTK2 (0.58) | HTTGAAHDAC2HDAC1LMNA | |
| SCHEMBL14289658 | 0.64 | ALDH1A1 (0.70) | HTTGAAUSP2ALOX15HSD17B10 | |
| SCHEMBL13831830 | 0.64 | PTK2 (0.83) | GAALMNAMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL13832014 | 0.61 | ALDH1A1 (0.48) | HTTGAAHDAC2HDAC1LMNA | |
| SCHEMBL25336347 | 0.61 | SMN1; SMN2 (1.00) | HDAC2HDAC1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL4217012 | 0.61 | POLB (0.67) | HTTGAAHDAC2HDAC1LMNA | |
| SCHEMBL15986468 | 0.60 | PTK2 (0.78) | HTTHSD17B10HDAC2LMNAMAPK1 | |
| SCHEMBL20813034 | 0.60 | MAPT (0.56) | HTTGAAUSP2HSD17B10LMNA | |
| SCHEMBL13832217 | 0.60 | MAPT (0.56) | HTTGAAUSP2HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | claimed |