Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778088 | 0.77 | HTT (0.45) | ALDH1A1NPSR1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL25336347 | 0.77 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2KMT2AADRB2L3MBTL1 | |
| SCHEMBL14289658 | 0.76 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2AMAPTL3MBTL1 | |
| SCHEMBL13831830 | 0.76 | PTK2 (0.83) | ALDH1A1NPSR1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL4217012 | 0.73 | POLB (0.67) | ALDH1A1SMN1; SMN2KMT2AMAPTL3MBTL1 | |
| SCHEMBL19420130 | 0.72 | L3MBTL1 (0.81) | ALDH1A1NPSR1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL4792669 | 0.72 | ALDH1A1 (1.00) | ALDH1A1NPSR1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL18389044 | 0.70 | ALDH1A1 (1.00) | ALDH1A1NPSR1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL15983775 | 0.70 | USP2 (0.61) | ALDH1A1SMN1; SMN2KMT2AMAPTL3MBTL1 | |
| SCHEMBL15986468 | 0.69 | PTK2 (0.78) | ALDH1A1SMN1; SMN2KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | claimed |
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | disclosed |