SCHEMBL4778227

SCHEMBL4778227

C=CCCCOC1(OCCCC=C)CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4778331 0.94 LPAR3 (0.37) ALDH1A1TSHRLPAR3LPAR2
SCHEMBL4775361 0.92 LPAR3 (0.40) ALDH1A1TSHRLPAR3LPAR2
SCHEMBL22856412 0.86 CA2 (0.32)
SCHEMBL4775263 0.75
SCHEMBL11303860 0.75
SCHEMBL31408699 0.75
SCHEMBL4781562 0.74 LPAR3 (0.36) ALDH1A1TSHRLPAR3LPAR2L3MBTL1
SCHEMBL14778086 0.73 MEN1 (0.35) ALDH1A1TSHR
SCHEMBL6161200 0.73 MEN1 (0.35) ALDH1A1TSHR
SCHEMBL14780056 0.73 MEN1 (0.35) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008004788-A1 NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF WONKISOPHARM CO., LTD. (KR) 2008-01-10 WO claimed
WO-2008004788-A1 NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF WONKISOPHARM CO., LTD. (KR) 2008-01-10 WO disclosed