Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778331 | 0.98 | LPAR3 (0.37) | LPAR3LPAR2TSHRALDH1A1 | |
| SCHEMBL4778227 | 0.92 | ALDH1A1 (0.32) | LPAR3LPAR2TSHRALDH1A1 | |
| SCHEMBL22856412 | 0.83 | CA2 (0.32) | — | |
| SCHEMBL1164717 | 0.81 | TSHR (0.39) | LPAR3LPAR2TSHRALDH1A1LMNA | |
| SCHEMBL4775373 | 0.75 | TSHR (0.35) | LPAR3LPAR2TSHRALDH1A1MAPT | |
| SCHEMBL4780035 | 0.75 | TSHR (0.35) | LPAR3LPAR2TSHRALDH1A1MAPT | |
| SCHEMBL4781283 | 0.75 | TSHR (0.35) | LPAR3LPAR2TSHRALDH1A1MAPT | |
| SCHEMBL4780400 | 0.74 | — | — | |
| SCHEMBL25722783 | 0.73 | TSHR (0.58) | TSHRALDH1A1 | |
| SCHEMBL6161219 | 0.72 | TSHR (0.36) | LPAR3LPAR2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | claimed |
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | disclosed |